Predicting the future is always a risky business. Still, we can observe developing trends in both our local natural conditions and those on a global scale. What might the Prairie State--which has already seen such dramatic transformations in the past two centuries--look like at the end of the next two? This talk, created specifically to honor the Illinois Bicentennial, incorporates latest findings in climatology, biology, and geology to offer informed analysis of the most possible futures for our state, and for our world at large.